[Comp-neuro] Cable Theory of Protein Polarization

A new cable theory of protein polarization where intracellular dendritic proteins play a role in spatiotemporal signaling and conduction. Write to me for a reprint.


JOURNAL OF INTEGRATIVE NEUROSCIENCE, Vol. 11, No.4 (December 2012)
http://www.worldscientific.com/toc/jin/0/0

Intracellular capacitive effects of polarized proteins in dendrites
R. R. Poznanski and L. A. Cacha

Passive dendrites become active as a result of electrostatic interactions by dielectric polarization in proteins in a segment of a dendrite. The resultant nonlinear cable equation for a cylindrical volume representation of a dendritic segment is derived from Maxwell's equations under assumptions: (i) the electric field is restricted longitudinally along the cable length; (ii) extracellular isopotentiality; (iii) quasi-electrostatic conditions; (iv) isotropic membrane and homogeneous medium with constant conductivity; and (v) protein polarization contributes to intracellular capacitive effects through a well defined nonlinear capacity-voltage characteristic; (vi) intracellular resistance and capacitance in parallel are connected to the membrane in series. Under the above hypotheses, traveling wave solutions of the cable equation are obtained as propagating fronts of electrical excitation associated with capacitive charge-equalization and dispersion of continuous polarization !
charge densities in an Ohmic cable. The intracellular capacitative effects of polarized proteins in dendrites contribute to the conduction process.

Keywords: Maxwell's equations: cable theory; polarization field; dendritic conduction; voltage-dependent capacitance; dielectric polarization


--------
Roman R. Poznanski
Professor
Office: D218(Block D)2nd Floor
Universiti Tunku Abdul Rahman (UTAR)
Department of Physical & Mathematical Science
Faculty of Science
31900 Kampar, Perak
Malaysia
Office: (+605)468-8888 Ext. 2289
E-mail: roman@utar.edu.my
http://romanpoznanski.blogspot.com
and
Chief-Editor,
Journal of Integrative Neuroscience
http://www.worldscinet.com/jin/mkt/editorial.shtml





+++++++++++++++++++++++++++++++++++++++++++++
++++++++++++++++++++++++++++++++++
This message is confidential and is solely intended for the
individual named. If you have received this e-mail in error
please notify the sender. Universiti Tunku Abdul Rahman
and/or the sender accepts no liability for any damages, claims
or losses caused by any viruses that may be transmitted by
this e-mail or any attachment. Any views or opinions
presented in this e-mail are solely those of the sender. No
contract or official order shall be concluded by means of this
e-mail.
+++++++++++++++++++++++++++++++++++++++++++++
++++++++++++++++++++++++++++++++++




+++++++++++++++++++++++++++++++++++++++++++++
++++++++++++++++++++++++++++++++++
This message is confidential and is solely intended for the
individual named. If you have received this e-mail in error
please notify the sender. Universiti Tunku Abdul Rahman
and/or the sender accepts no liability for any damages, claims
or losses caused by any viruses that may be transmitted by
this e-mail or any attachment. Any views or opinions
presented in this e-mail are solely those of the sender. No
contract or official order shall be concluded by means of this
e-mail.
+++++++++++++++++++++++++++++++++++++++++++++
++++++++++++++++++++++++++++++++++




+++++++++++++++++++++++++++++++++++++++++++++
++++++++++++++++++++++++++++++++++
This message is confidential and is solely intended for the
individual named. If you have received this e-mail in error
please notify the sender. Universiti Tunku Abdul Rahman
and/or the sender accepts no liability for any damages, claims
or losses caused by any viruses that may be transmitted by
this e-mail or any attachment. Any views or opinions
presented in this e-mail are solely those of the sender. No
contract or official order shall be concluded by means of this
e-mail.
+++++++++++++++++++++++++++++++++++++++++++++
++++++++++++++++++++++++++++++++++

_______________________________________________
Comp-neuro mailing list
Comp-neuro@neuroinf.org
http://www.neuroinf.org/mailman/listinfo/comp-neuro