[Comp-neuro] PhD position in computational neuroscience (Goethe University Frankfurt)

Applications are invited for a 3-year PhD position to work with Dr.
Peter Jedlicka at Goethe-University Frankfurt in an NSF & BMBF funded
US-Germany project aimed at understanding how chloride dynamics affect
cerebellar computation. This project is in collaboration with Dr.
Fidel Santamaria at The University of Texas at San Antonio and Dr.
Thomas Kuner at Heidelberg University. The PhD student will be
involved in the generation and implementation of computational models
focusing on chloride-dependent changes in cerebellar inhibition. The
student will be using computer simulations to reproduce/predict data
from electrophysiology experiments on neurons expressing diverse
fluorescent molecules that report chloride concentrations. Visits to
US for short-term and long-term periods of time to learn techniques
and exchange information are part of the activities of this grant. The
successful candidate should have a background in physics, mathematics,
engineering or computational neuroscience. Experience in scientific
programming is highly desirable. The appointment will be starting in
November/December 2012.

Please submit a CV and statement of research interests to:

Dr. Peter Jedlicka (jedlicka@em.uni-frankfurt.de)
NeuroScience Center
Clinical Neuroanatomy (Anatomy I)
Theodor-Stern-Kai 7
Goethe-University
60590 Frankfurt
Germany

The project is related to these recent publications:

Jedlicka P, Deller T, Gutkin BS, Backus KH (2011) Activity-dependent
intracellular chloride accumulation and diffusion controls GABA(A)
receptor-mediated synaptic transmission. Hippocampus 21:885-98.

Santamaria F, Wils S, De Schutter E, Augustine GJ (2011). The
diffusional properties of dendrites depend on the density of dendritic
spines. Eur. J. Neurosci. 34:561-8.

Coop AD, Cornelis H, and Santamaria F (2010). Dendritic excitability
modulates dendritic information processing in a Purkinje cell model.
Front. Comput. Neurosci. 4:6. doi:10.3389/fncom.2010.00006.

Santamaria F, Wils S, De Schutter E, Augustine GJ (2006). Anomalous
diffusion in Purkinje cell dendrites caused by spines. Neuron
52:635-648.

Dübel J, Haverkamp S, Schleich W, Augustine GJ, Feng G, Kuner T, Euler
T (2006). Two-photon imaging reveals somato-dendritic chloride
gradient in retinal ON-type bipolar cells expressing the biosensor
Clomeleon. Neuron 49, 81-49.

P.S. If you are interested and will be attending FENS 2012 in
Barcelona just send me an email or give me a call so that we can meet
and talk.


--
Peter Jedlicka, MD, PhD
NeuroScience Center
Clinical Neuroanatomy (Anatomy I)
Goethe-University
Theodor-Stern-Kai 7
D-60590 Frankfurt am Main
Phone: ++49 (179) 238 6269
Fax: ++49 (69) 6301 6425
Email: jedlicka@em.uni-frankfurt.de
http://peterjedlicka.googlepages.com




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